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Los números apuntan a hombres jóvenes, sin apenas formación, que viven en hogares monoparentales y tienen una vida laboral inestable. Víctor Agulló, quien ha recopilado algunas de estas cifras, es autor de una tesis que aborda el uso de los esteroides en deportistas amateurs. «Cada vez es más frecuente que el consumo se dé en distintos sectores de la población, independientemente del grupo social al que pertenezcan» aunque afirma que, «si hay algo que les une, es que priorizan el bienestar físico ante cualquier otra opción». Entre el resto de comportamientos generalizados, Agulló destaca «los cuidados como la depilación o los tratamientos de bronceado». La práctica ilegal consistía en pasar consulta a deportistas, culturistas generalmente, en una clínica podológica, por parte de un médico sirio y recetarles anabolizantes y otros medicamentos para su implementación muscular y mayor rendimiento físico, sin justificación terapéutica.
Suplementos de calcio como adyuvante del tratamiento específico en la prevención y tratamiento de la osteoporosis (A). La información disponible en cada una de las fichas del Pediamécum ha sido revisada por el Comité de Medicamentos de la Asociación Española de Pediatría y se sustenta en la bibliografía citada. Estas fichas no deben sustituir en ningún caso a las aprobadas para cada medicamento por la Agencia Española de Medicamentos y Productos Sanitarios (AEMPS) o la Agencia Europea del Medicamento (EMA). Se aconseja la inducción de pubertad con dosis bajas sistémicas de estradiol (por ejemplo, parches con dosis bajas) y aumentar la dosis de forma progresiva durante un periodo de 3-4 años, siendo el objetivo maximizar la talla final adulta y el pico de masa ósea.
Podría enmascararse el resultado con la administración simultánea de epitestosterona. Como se señaló anteriormente, los andrógenos estimulan la eritropoyesis, produciendo un aumento del hematocrito y la hemoglobina, debido a una mayor sensibilidad para la eritropoyetina y a una supresión en la transcripción de hepcidina61. Una complicación típica con los agentes alquilados es la peliosis hepática, caracterizada por la formación de cavidades quísticas que pueden producir insuficiencia hepática y hemorragias internas10,fifty five.
Todos estos trastornos psiquiátricos se relacionan con alteraciones en neurotransmisores como la serotonina y el ácido gamma-aminobutírico42. Las dosis suprafisiológicas de anabolizantes ejercen una neurotoxicidad con apoptosis de células neuronales y la posibilidad de desarrollar déficits cognitivos43. Los andrógenos pueden administrarse como testosterona transdérmica en gel o parches. Su vida media es corta por lo que se prefieren las formas de ésteres de testosterona en el grupo 17 β-hidroxilo en forma oleosa por vía parenteral (propionato, enantato, cipionato, undecanoato) para prolongar su actividad. Otra forma de administración es en forma cíclica (cycling) con períodos de descanso. En este período de descanso, muchos utilizan tamoxifeno y hCG para tratar de recuperar la función testicular13.
Se observó un gran número estudios que hablan sobre los EAA en culturistas en comparación con otros deportistas de fuerza/potencia, esto es debido, como cuenta Hoffman y Ratamess1 en su revisión, a que la mentalidad y la motivación de estos deportistas son muy distintas. En contraste, los culturistas, usan los agentes anabólicos para aumentar el crecimiento muscular y favorecer su definición, combinan la toma de los agentes anabólicos con otras sustancias como diuréticos, hormonas tiroideas, anti-estrogénicos, etc. Los expertos de la escuela m�dica Harvard (Boston, EEUU) reclutaron a 19 deportistas de un gimnasio, todos eran hombres y levantadores de peso. Doce afirmaron haber consumido esteroides anabolizantes androg�nicos (testosterona y sustancias derivadas) para aumentar la masa muscular. La dosis media fueron 675 miligramos semanales de la citada hormona masculina durante 468 semanas. Uno de los principales efectos adversos de los agentes anabólicos son los que producen dichas sustancias sobre el sistema cardiovascular.
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